Does Cuban Scorpion Venom Cure Cancer?

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Does Cuban Scorpion Venom Cure Cancer?

Preparations based on blue scorpion venom have been, and still are, sold illegally. They have not been authorized by any international regulatory agency and there is no scientifically proven evidence of their effectiveness.

The venom of a rare blue scorpion found only in Cuba (Rhoplaorus junceus) is considered a product of natural origin for cancer therapy. The biologist Misael Bordier was the first to describe its effects in 1985. The poison extract was marketed by a Cuban pharmaceutical company in two different formulations, a solution and a homeopathic formulation. In Europe it is produced by a company transplanted to Tirana.
Preparations based on blue scorpion venom have been, and still are, sold illegally as they have not been authorized by any international regulatory agency.
According to the manufacturers, the poison has anti-inflammatory, pain-relieving, immunoregulatory and anticancer effects. The website advertising the homeopathic version states that 60,000 people have been treated with scorpion venom but, to date, the results of so-called "controlled" clinical studies have never been published in any international scientific journal, that is to say clinical trials in which one part of the patients receive the treatment under consideration and another part a standard treatment, placebo or other comparator treatment.
There are only two studies on scorpion venom in the literature and they have come to opposite conclusions. The first demonstrates the ability of a poison extract to kill cancer cells in vitro (i.e. test tube cultured cells); the second, on the contrary, highlights how the poison extract increases the growth and invasiveness of liver tumor cells (always in test tubes).
Basically, there is a lack of sufficient scientific evidence to prove the efficacy of scorpion venom extracts as anticancer therapies.
It is therefore advisable to rely only on therapies whose safety and efficacy are published in international scientific journals and which have been authorized and approved by drug evaluation agencies, such as AIFA for Italy, EMA for Europe, FDA. for the United States.

1. Díaz-García A, Morier-Díaz L, Frión-Herrera Y, Rodríguez-Sánchez H, Caballero-Lorenzo Y, Mendoza-Llanes D, Riquenes-Garlobo Y, Fraga-Castro JA. In vitro anticancer effect of venom from Cuban scorpion Rhopalurus junceus against a panel of human cancer cell lines. Journal of Venom Research. 2013; : 5-12
2. Giovannini C, Baglioni M, Baron Toaldo M, Cescon M, Bolondi L, Gramantieri L. Venom from Cuban Blue Scorpion has tumor activating effect in hepatocellular carcinoma. Scientific Report. 2017; : 44685

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